The 4 Best Milk Thistle Supplements In 2022 (2023)

Are you looking for a natural supplement that could boost your overall health? You might have already heard about the detoxifying properties of milk thistle. It is a powerful dietary supplement that is taken orally and is used to treat various health issues. The supplement is extracted from the seeds of the milk thistle plant or Silybum marianum, and its active ingredients are collectively called ‘Silymarin.’

Due to its antioxidant and anti-inflammatory properties, the supplement is gaining popularity for treating liver disorders, especially fatty liver disease. Besides that,such supplement can also treat hepatitis, diabetes, gallbladder issues, jaundice, and cirrhosis.

So if you’re considering buying such supplement to treat your health problems, you’re in the right place. This guide will go through the top four milk thistle supplements and an informative buying guide and FAQs section.

Our Top Picks For The Best Milk Thistle Supplements

  1. Herbal Roots Milk Thistle – Overall Best Milk Thistle Supplements, Editors Choice
  2. Herb Pharm Liquid Herbal Extract – Most Recommended Milk Thistle Brand For Liver Health
  3. Puritan’s Pride Milk Thistle – Gluten Free Supplement Brand With Different Flavors
  4. Herb Pharm Milk Thistle – Best Premium Brand For Boosting Detoxification & Blood Sugar

#1. Herbal Roots Milk Thistle – Overall Best Milk Thistle Supplements, Editors Choice

The 4 Best Milk Thistle Supplements In 2022 (1)

Herbal Roots Milk Thistle is a high-quality and potent supplement that detoxifies the body and helps prevent the formation of free radicals in the body. These capsules are pure organic seeds extract and powder. Such extract in these capsules also promotes healthy liver function and reduces further liver damage.

This supplement is manufactured by Herbal Roots, a well-known health and wellness company in the U.S. It is a small family-owned business that focuses on providing natural and drug-free alternatives to people to treat various health issues. It manufactures its supplements in GMP-certified facilities, and they also test its products for quality assurance. In addition, these products do not have any fillers, additives, or harmful chemicals.

Besides improving digestion and providing liver support, such provides youthful skin and a healthy body. The antioxidants in this thistle reduce the free radicals in the body and prevent them from damaging the skin. This way, it helps in keeping the skin healthy and youthful.

The thistle is safe to consume for several months daily, but there are a few side effects too. If you’re allergic to daisies, kiwi, artichokes, chrysanthemums, and marigolds, you might be at a higher risk of side effects. Besides that, there might be drug interactions, too, if you’re on certain medications. Thus it is important to rule it out.


Ingredients: The thistle capsules by Herbal Roots consist of extract that has 80% silymarin. Moreover, the ingredients are vegan and pure, and there are no fillers, additives, or binders. Each capsule also contains thistle seed extracts and 80% standardized Silymarin.

Digestive Support:Such supplements stimulate digestion by supporting the digestive juices in the stomach. The supplement’s healthy nutrients and powerful ingredients work along the enzymes, bile, and other stomach acids to improve digestion.

Liver Support: Herbal Roots milk thistle acts as a powerful liver aid. It has anti-inflammatory and antioxidant characteristics that cleanse the liver and remove toxins. Besides that, such capsules also reduce liver damage/

(Video) Best Silymarin 2022 (TOP5)

Transparency: The brand conducts tests to prove the purity and potency of the product. Their product has all the ingredients and information on its label. The official website has a detailed FAQs section that helps the users continue using the supplement safely.

Directions: According to the manufacturer, you have to consume one capsule two to three times daily. Each bottle of this supplement contains 60 capsules, and according to the dosage, it takes around one month to finish the bottle. You can take the supplement daily for up to 41 months.


  • Pure and organic milk thistle seeds
  • Effective and high-quality ingredients
  • GMP-certified facilities
  • Non-GMO and gluten-free
  • Tested for quality and potency
  • Free delivery on orders over $50
  • 100% no-risk money back guarantee


  • A few side effects such as diarrhea and bloating

=> Click here to visit the official website of Herbal Roots

#2. Herb Pharm Milk Thistle Extract – Most Recommended Milk Thistle Brand For Liver Health

The 4 Best Milk Thistle Supplements In 2022 (2)

Herb Pharm Milk Thistle is a great supplement if you want a natural and organic supplement that offers a good dose of Silymarin. The supplement is in extract form and is taken from dried pericarp (seed coat) of Silybum marianum. This Thistle is manufactured by Herb Pharm, a reliable name in the health and wellness industry. The company manufactures high-quality herbal extracts to help people heal. Besides that, the company keeps educating people about its herbal supplements safe use.

The company offers more than 160 herbal supplements and 85 proprietary blends as health supplements. Their supplements are helping people to improve their physical and mental health naturally. The thistle extract contains Silybum marianum extracts from organically grown plants. These plants are ethically sourced from around the world.

The thistle extract by Herb Pharm is made up of certified organic, non-GMO, vegan, and gluten-free ingredients. The company is Bee Friendly Certified and Salmon-Safe certified. Moreover, it is a United Plant Savers member.


Manufacturing Process: The manufacturer uses a triple percolation and double extraction process to produce a concentrated extract without heat. The process ensures that the extract contains the Silymarin flavonoids in the broad spectrum of Milk Thistle. These flavonoids are silybin, silychristin, and silydianin.

High-Quality Formula: The Herb Pharm Thistle extract consists of Certified and organically grown Silybum Marianum. Besides the main active ingredients, its formula includes grain alcohol and distilled water.

Health Benefits: The supplement is minimally processed, and its ingredients are closer to nature. There are no preservatives and additives, as claimed by the company, and the extract promotes fast absorption. The supplement has a soapy and sharp taste but has many health benefits. Due to its fast absorption, the supplement reaches your blood quickly and starts detoxifying the body for improved liver health.

Flexible Use: The herbal dietary supplement comes in a small bottle that contains one fluid ounce (29.5 ml) of thistle extract. The liquid herbal extract can be used orally by the bottle’s dropper.

(Video) Countdown of 10 Best Milk Thistle Supplements

Dosage: To use the extract, shake it well and open it. Squeeze the dropper bulb and drop a full squeeze of it into at least two oz. Of water or juice. You can take this supplement two to four times daily between meals. For best results, read the instructions on the label properly.


  • Naturally sourced and grown
  • Promotes liver health
  • Promotes detoxification
  • Non-GMO, Gluten-free, and Vegan
  • Fast absorption
  • Easy to use
  • Guaranteed secure shopping
  • Ships within 1 to 2 business days


  • It contains an ingredient that doesn’t comply with Prop 65

=> Click here to visit the official website of Herb Pharm

#3. Puritan’s Pride Milk Thistle – Gluten Free Supplement Brand With Different Flavors

The 4 Best Milk Thistle Supplements In 2022 (3)

Puritan’s Pride Milk Thistle supports liver health, and it is an antioxidant that fights free radicals and reduces oxidative stress on the body. Besides that, the antioxidant characteristics of the thistle can fight against various diseases to improve overall health and wellness. The supplement contains concentrated forms of antioxidants that boost overall health by neutralizing free radicals.

The manufacturer of this brand Puritan’s Pride, has more than 45 years of experience in the health supplements industry. Their supplements and multivitamins are made of high-quality natural ingredients at affordable prices.

This product contains no preservatives, sugar, artificial flavors, gluten, yeast, or wheat. The best thing about this supplement is that it is very easy to use. You can also swallow it with water, open the capsule, and use the extract to make thistle tea.


Source: The Puritan’s Pride is taken from a purple flower which was a part of Greek medicine centuries ago. Besides that, the soft gels contain Silybum marianum seed 4:1 extract equivalent to 1000 mg. Other ingredients include soybean oil, vegetable glycerin, gelatin, paprika, and soy lecithin.

Dosage: According to the manufacturer, you can take one softgel once or twice daily. There are 90 softgels in one bottle, which is enough for one and a half-month supply. However, the softgels are available in different sizes too, which include 30 and 180 softgels.

Quality Tested: Puritan’s Pride tests its products for purity and potency throughout the manufacturing process and after that. The company conducts around 15 quality tests for each product, so customers shop confidently.

Contraindications: You shouldn’t consume such a supplement if you are pregnant, nursing, or have a medical condition. If you are using medicines or have an allergy to certain ingredients, you must consult a medical professional before taking a milk thistle supplement. You shouldn’t use this supplement if you are under 18 years.


  • Contains antioxidant characteristics
  • Promotes liver repair
  • No artificial flavors
  • Gluten-free
  • Rapid release
  • Pure and concentrated extract
  • Reputable brand


  • The soft gels melt easily
  • Contains gelatin

=> Click here to visit the official website of Puritan’s Pride

(Video) When to Take Milk Thistle

#4. Herb Pharm Milk Thistle – Best Premium Brand For Boosting Detoxification & Blood Sugar

The 4 Best Milk Thistle Supplements In 2022 (4)

This Milk Thistle by Herb Pharm is specially designed for cleansing and detoxification. The manufacturer takes the ingredients from their Certified Organic Farms and gathers the herbs from various reliable sources worldwide. The company manufactures its health supplements in the Oregon countryside, where they grow more than 75 herbs to create health and wellness supplements. The company also relies on growers, wildcrafters, and brokers to collect the best ingredients.

This is a liquid extract and comes in a bottle with a dropper bulb. Moreover, the supplement is very easy to use and is powerfully effective. It contains a broad spectrum of milk seeds, allowing the supplement to work smoothly and effectively. It is easily digestible and has an excellent absorption rate compared to other supplements. To use the milk extract, add it to water or juice to your daily routine for the best results.


Ingredients: Milk Thistle has an extraction rate of 2100 mg herb per 0.7 ml. The supplement contains thistle seed (Silybum marianum), certified organic cane alcohol, and distilled water. Besides that, it has herb menstruum in the ratio of 3:1.

Effectiveness: If you focus on cleansing and detoxifying the liver, the Herb Pharm Thistle is a perfect choice. The ingredients in the supplement are highly effective and digestible. Plus, the supplement is dairy, gluten, and peanut-free, thus suitable for everyone.

Instant Absorption: Milk extracts offer fast absorption as they are readily absorbed and easily digested. So, if you’re looking for a milk supplement that offers fast absorption, the liquid extract form is best for you.

Dosage: You can use the milk extract by adding a fully squeezed dropper into two oz juice or water. For best results, start with a lower dose and look for any side effects. You can then gradually increase for quicker results.


  • Certified organic and gluten-free
  • Herbal identity assured
  • Vegan and non-GMO
  • Easy to use the dropper bottle
  • Concentrated extract
  • No dietary restrictions


  • Less desirable after-taste

=> Click here to visit the official website of Herb Pharm

How We Made The List Of Best Milk Thistle Supplements?

There are lots of companies that claim that their products are best for treating several ailments. However, not all are created equal because not all manufacturers follow good manufacturing practices. Though milk thistle has been used as an ailment for centuries, these days, brands may use additives and artificial ingredients to back up their claims. Thus, we researched online to find the best thistle supplement available.

We considered various factors in choosing the best supplements on the market. For instance, we carefully evaluated the ingredients, dosage, brand reputation, and transparency.

What We Looked For?

  • Active Ingredient: Silymarin is the active ingredient in milk thistle and has several benefits. The ingredient acts as an antioxidant and improves liver detoxification. For the supplement to be effective, it should contain the right amounts of Silymarin. Thus, we checked the supplements’ labels and followed the silymarin content in each.
  • Supplement Form: Such supplements are available in different forms, for instance, milk thistle tablets, drops, and extracts. We have chosen different products so that our readers choose the one that suits them best.
  • Transparency: For a health supplement, the brand must be transparent about its ingredients, manufacturing processes, and extraction methods. We have considered only those brands that are more open about the ingredients of their supplements. Plus, we made sure that the supplements were manufactured in FDA-approved facilities.
  • Customer Reviews: We read hundreds of customer reviews to ensure that the brands we choose have the majority of satisfied customers. We could also determine the brands’ reliability and effectiveness through the reviews.

Buying Guide: How To Choose The Best Milk Thistle Brand?

Since the market is overloaded with numerous milk thistle brands, you must learn to differentiate between a defective product and a good quality milk thistle. To help you choose the best milk thistle supplement, we have jotted down a list of factors. Following are the things you should look for in the best thistle product:

(Video) 8 Benefits of Milk Thistle for the Liver

  • Third-Party Tests

Most brands claim that their milk thistle products are natural and safe to consume. But what is the proof to back their claims? Third-party tests allow the users to go through the lab reports for products and ensure that the ingredients are safe to consume and potent enough to be effective.

  • Factory Certifications

You must also ensure that the such supplements are created in certified factories and facilities. Health and wellness supplements should be manufactured in FDA-approved and GMP-certified facilities, and the products manufactured in such facilities are reliable and safe for consumption.

  • Dosage

For a thistle supplement to be effective, it must contain around 70 to 80% Silymarin content per 100 to 300 mg. For thistle tablets or capsules, if the Sylimarin content is 70 to 80% per 100 to 300 mg in a capsule, it is very effective. You can take around two to three such capsules for the best results.

  • Side Effects

Always check the side effect narration of the brand or warnings before purchasing it. Though a good quality thistle will have minimum side effects, it can still have a few, which you must consider before consuming. A few potential side effects of thistle include a ragweed allergy.

  • Health Benefits

Besides treating liver disorders, quality thistle will also offer numerous health benefits.In addition, it is considered one of the best liver detox supplements that cleanse the liver and offer healthy well being. You must look for supplements that offer other potential benefits such as soothing skin inflammation, antiviral and antibacterial properties, Age-related effects, and improved bone health.

FAQs Related To Milk Thistle Supplements

What Is Milk Thistle?

Milk Thistle is a herb with seeds used to make such supplements. The thistle seeds contain a powerful natural antioxidant called Silymarin which can treat various health issues, especially liver diseases.

The ingredients in such supplements work together to destroy the free radicals in the body and improve body functions. The free radicals in the body are responsible for causing cancer and other types of diseases. Besides that, free radical damage also accelerates the aging process. Milk thistle can slow the process of aging as it has antioxidant properties.

How Much Milk Thistle Should I Consume?

The dosage of such products varies from brand to brand, but you can consume around 300 mg to 1000 mg of milk thistle throughout the day. The FDA doesn’t recommend any dosage for such products, and thus it is important to read the instructions on the product’s label. If you’re still unsure of the dosage, you must consult your doctor to determine the most suitable dosage for you.

What Is The Best Way To Consume Milk Thistle?

Milk thistle products are available in various forms, which include tablets, capsules, gels, and extracts. All these forms have pros and cons, which ultimately depend on your preference. Such thistle extracts offer fast absorption but have a bitter taste, which might be a con for many people.

On the other hand, capsules and tablets aren’t tasty, but they don’t have a bitter after-taste compared to extracts. Capsules and tablets take more time to break down as compared to extracts. In short, extracts are considered more effective than capsules and pills.

(Video) 4 Most Liver Damaging Supplements (Avoid Over Usage)

Conclusion: Which Brand Offers The Best Milk Thistle?

We hope our reviews for the best milk thistle supplements will help you choose the best one according to your requirements. Such supplements promote detoxification, improve liver function, support cholesterol metabolism, support weight loss, and help control diabetes.Moreover, refer to this guide if you want to know how to detox your liver at ease.

If you have decided to focus on your health and fitness, you must try the milk thistle supplements. However, it is always important to consult your healthcare provider before starting a supplement, even if it’s a herbal supplement.


What brand of milk thistle is the best? ›

The Best Milk Thistle Supplements
  • Best Overall. Puritan's Pride Milk Thistle. Affordable Six Month Supply. ...
  • Best Antioxidant Formula. Jarrow Formulas Milk Thistle. ...
  • Strongest Dose. Fresh Nutrition Milk Thistle Capsules. ...
  • Best for Liver Health. FarmHaven Milk Thistle Capsules. ...
  • Most Trusted. Nature's Bounty Milk Thistle Capsules.
13 Feb 2020

What is the strongest milk thistle you can buy? ›

New Strongest 10,000mg Organic Milk Thistle 20:1 Extract 80% Silymarin Super Potent Formula; After the success of our best-selling 2000mg organic milk thistle formula we decided to 5x the strength to bring you to our knowledge the first 10,000mg version on the market!

What kind of milk thistle should I buy? ›

Milk thistle extract is a powerful supplement that can benefit health, especially liver health. The key to choosing the best milk thistle supplements is to look for a standardized silymarin phytosome.

What is the best amount of milk thistle to take? ›

There is no standardized dosage or recommended intake for milk thistle tea, but it's generally considered safe if consumed in moderation. Milk thistle supplements, for reference, are tolerated at doses of up to 700 mg, 3 times per day for 24 weeks ( 1 ).

What is the best milk thistle to take for liver? ›

Top Rated
  • Nature's Bounty Milk Thistle Capsules 250mg, 200CT. Nature's Bounty. ...
  • Nature's Truth Milk Thistle Seed Extract 1,000 mg. Nature's Truth. ...
  • Irwin Naturals Milk Thistle Liver Detox plus BioPerine Softgels, 60CT. Irwin Naturals. ...
  • CVS Health Milk Thistle Capsules, 200CT. ...
  • Nature's Bounty Milk Thistle Caplets 175mg, 100CT.

Is it better to take milk thistle at night or morning? ›

Milk thistle is generally tolerated well by the body, meaning you can take it pretty much whenever you want. It won't keep you awake at night, it can be taken on an empty stomach or combined with meals as an added ingredient, and there isn't a particular time of day where it's more potent or effective.

What medications should not be taken with milk thistle? ›

Possible interactions include:
  • Cytochrome P450 2C9 (CYP2C9) substrates. Taking milk thistle might affect this enzyme and drugs it processes, such as diazepam (Valium), warfarin (Jantoven) and others. ...
  • Diabetes medications. ...
  • Raloxifene (Evista). ...
  • Simeprevir. ...
  • Sirolimus (Rapamune).

How much milk thistle should I take for fatty liver? ›

Milk thistle is marketed as capsules or tablets containing ethanol extracted silymarin in amounts of 250 to 750 mg and is purported to be beneficial for liver disease, including alcoholic and viral liver disease. The daily dosage varies but it is typically taken 2 to 3 times daily.

What happens if you take milk thistle everyday? ›

Milk thistle is generally considered safe for most people at dosages up to 420 mg 3 times a day. However, it may cause allergic reactions, such as itching, headaches, and joint pain, or gastrointestinal symptoms like nausea or diarrhea.

How much milk thistle should you take daily for liver health? ›

If you're taking milk thistle for the liver, the recommended daily intake of milk thistle is 150 milligrams, taken one to three times daily. This is a somewhat high dose that can act as a natural liver detox. For ongoing use and liver support, take 50 to 150 milligrams daily.

How much milk thistle is recommended daily? ›

For diabetes: Milk thistle extract 210-600 mg has been used daily for up to 6 months. 200 mg of milk thistle extract has been taken once daily or three times daily for 4 months to one year.

What is the best time to take milk thistle capsules? ›

Milk thistle can be taken on an empty stomach. Some believe this makes it work faster; however, very sensitive individuals should consider taking milk thistle with a meal instead. Milk thistle can be taken in herbal capsules or liquid extracts.

Can milk thistle reverse liver damage? ›

Milk thistle will not reverse existing liver damage, and it will not cure infection with the hepatitis B or hepatitis C virus. Milk thistle should not be used by people who have complications from cirrhosis (such as variceal bleeding or ascites).

Can milk thistle reverse fatty liver? ›

Medical research on milk thistle and liver health has led to mixed results. Studies show that silymarin may help ease inflammation and promote cell repair. This may help ease symptoms from liver diseases like jaundice, cirrhosis, liver cancer, and fatty liver disease.

How much milk thistle should I take for liver cirrhosis? ›

One source suggests daily doses of 12 to 15 g of dry fruits for dyspepsia and disorders of the biliary system, while an extract containing 200 to 400 mg/day of silymarin is considered effective in various liver disorders.

Can milk thistle detox your liver? ›

Consider using a potent milk thistle extract to protect and detox the liver. This fantastic natural herb helps young persons maintain liver health. And after age 40, the detox power of the liver slows down. So regardless of age, milk thistle aids with prevention as well as repair.

Does milk thistle affect sleep? ›

Sleep quality also improves. The effect of taking milk thistle by itself is not known. Multiple sclerosis. Early research suggests that taking a combination supplement containing silymarin, a chemical found in milk thistle, can improve mental function and promote disease stabilization in people with multiple sclerosis.

What does milk thistle cure? ›

Historically, people have used milk thistle for liver disorders and gallbladder problems. Milk thistle is promoted as a dietary supplement for hepatitis, cirrhosis, jaundice, diabetes, indigestion, and other conditions.

Why you should not take milk thistle? ›

Milk thistle can trigger allergic reactions. People who are allergic to artichokes, kiwi, ragweed, daisies, marigolds, and chrysanthemums are at higher risk. People who have diabetes or endometriosis should check with a doctor before using milk thistle.

Can I take milk thistle with vitamin d3? ›

No interactions were found between milk thistle and Vitamins.

Does turmeric interact with milk thistle? ›

No interactions were found between milk thistle and turmeric.

Is milk thistle good for kidneys? ›

Milk thistle (Silymarin marianum) is a well-known herbal therapeutic commonly used for liver support. It supports detoxification through enhancing liver as well as kidney and pancreatic function.

What does milk thistle do to the brain? ›

Improves cognition. A 2015 study in worms found that milk thistle increased resistance to oxidative stress. Oxidative stress is a potential cause of Alzheimer's disease. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind.

How can I quickly repair my liver? ›

Focus on a healthy diet

getting sufficient fiber from sources like whole grains as well as fresh fruits and vegetables. choosing lean protein sources, such as seafood, skinless poultry, or legumes, as opposed to fattier meats. reducing your intake of foods or drinks that are high in sugars, salt, or unhealthy fats.

How can I detox my liver in 3 days? ›

The 3-day detox juice cleanse involves consuming only blended juices and water for 3 days.
In general, the following steps are taken in a specific order:
  1. Morning detox tea.
  2. Breakfast drink.
  3. Supplements.
  4. Lunch drink.
  5. Supplements (multivitamins, omega-3 fatty acids, and probiotics)
  6. Snack drink.
  7. Dinner drink.
  8. Detox ultra-bath.
8 Mar 2022

Can a damaged liver regrow? ›

The liver has a unique capacity among organs to regenerate itself after damage. A liver can regrow to a normal size even after up to 90% of it has been removed. But the liver isn't invincible. Many diseases and exposures can harm it beyond the point of repair.

Who should not use milk thistle? ›

Before taking milk thistle, talk to your doctor, pharmacist, or health care professional if you have allergies (especially to plants), have any medical conditions, or if you take other medicines or other herbal/health supplements. Milk thistle may not be recommended in some situations.

What are the dangers of milk thistle? ›

Milk thistle seems to have few side effects, even when taken for several years. Some people have nausea, diarrhea, itching, and bloating. Interactions. If you take any medicines regularly, talk to your doctor before you start using milk thistle.

Does milk thistle help repair the liver? ›

Liver healing and regeneration

Milk thistle helps stop oxidative stress and free radical damage in the liver. Research shows milk thistle restores damaged cells. Silymarin also protects the liver against damage from alcohol and some prescription drugs.

How long can you take milk thistle safely? ›

Milk thistle is considered safe in dosages of 420 mg/day orally in divided doses for up to 41 months.

Is it best to take milk thistle on an empty stomach? ›

How do I take milk thistle? Milk thistle can be taken on an empty stomach. Some believe this makes it work faster; however, very sensitive individuals should consider taking milk thistle with a meal instead. Milk thistle can be taken in herbal capsules or liquid extracts.


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