The 10 Best Milk Thistle Supplements (2023)

Which are the best milk thistle supplements?

Milk thistle, or Silybum Marianum (Silymarin), is a plant that’s been used for centuries as a natural remedy for liver disease.

The silymarin seeds are believed to contain a mixture of antioxidant, antiviral, and anti-inflammatory properties, which are thought to help lower cholesterol, detoxify the liver, and support overall liver health.

So, if you’re thinking of trying milk thistle for yourself, here’s a list of the 10 best milk thistle supplements on the market right now!

Top 10 Milk Thistle Supplements Compared

The list of milk thistle supplements and figures mentioned below has been compiled from various web sources.

These are the 10 best milk thistle supplements:

In A Rush? Here’s Our Top Pick:

High Potency Milk Thistle Capsules (120 Count)

$29.99

Buy Now

We earn a commission if you click this link and make a purchase at no additional cost to you.

10. Nature’s Answer – Milk Thistle Extract

Nature’s Answer Milk Thistle Extract is a liquid liver cleansing and detoxification supplement.

(Video) Countdown of 10 Best Milk Thistle Supplements

Each bottle provides you with 30 servings, all containing 2,000mg of pure milk thistle seed extract.

The supplement has undergone a process of “cold extraction,” which allows its raw materials to be extracted without heat exposure, letting the herb’s holistic balance be preserved.

According to Nature’s Answer, the super-concentrated formula promotes healthy liver function, detoxification, and waste elimination.

By taking milk thistle extract in liquid form, the brand suggests that it’s absorbed faster than capsules or tablets.

The supplement is 100% gluten and alcohol-free, non-GMO verified and made in the United States of America.

Nature’s Answer recommends taking 1 – 2ml (28-56 drops) three times a day with water for best results.

9. Bronson – Milk Thistle

Bronson’s milk thistle extract is a powerful antioxidant-fortified with dandelion root to promote healthy liver function.

You’ll receive 120 capsules/servings per bottle, each containing 1,000mg of milk thistle extract and 5mg of dandelion root.

Bronson suggests that the highly potent antioxidant helps maintain liver function, removes unwanted toxins, and converts nutrients into substances the body can use.

The supplement is formulated using the best ingredients in a cGMP-certified facility and lab-tested to ensure quality and potency.

The brand has been providing quality supplements since 1960 and has a proven record of offering the purest, high-quality vitamins backed by science.

Bronson recommends taking one capsule a day to get the most bang for your buck, preferably with a meal, to help absorption.

8. OmniBiotics – Organic Milk Thistle

OmniBiotics organic milk thistle utilizes a higher concentrate and is one of the strongest liver detoxification supplements available.

Inside each bottle, you’ll receive 120 capsules/servings, all containing 375mg of organic milk thistle seed extract, which is equivalent to 1,500mg of milk thistle.

According to the brand, taking the milk thistle can help support liver health and function, fight free radicals, boost the immune system, and support weight loss.

The clinical-strength organic supplement is 100% natural and free from gluten, animal by-products, artificial ingredients, chemicals, preservatives, and fillers.

It’s sourced and manufactured in the USA and has undergone extensive qualification processes to be certified organic.

(Video) Milk Thistle Liver Detox Side Effects

For best results, OmniBiotics recommends taking one capsule once or twice daily with a meal.

7. Toniiq – Ultra High Strength Milk Thistle

Toniiq’s ultra-high-strength capsules contain a greater milk thistle concentration than most competing products on the market.

Each tub comes with 90 capsules/servings; all containing 500mg of milk thistle concentrated seed extract or 25,000mg of milk thistle.

Toniiq uses high-quality milk thistle extract from ethically sourced family-owned farms tested for quality and purity during and after manufacturing.

The brand suggests that using a higher concentrated milk thistle supplement can lead to better absorption and bioavailability and more potent liver support.

Toniiq recommends taking one capsule one to three times daily for best results.

6. Zazzee Naturals – Organic Milk Thistle

Zazzle Naturals organic milk thistle extract supports healthy liver function and contains 80% Silymarin flavonoids.

Inside each bottle, you’ll receive 120 capsules/servings, all containing 7,500mg of organic milk thistle.

The powerful concentrated formula utilizes a 30:1 extract, meaning approximately 30 grams has been condensed into a single gram, making it 30x more potent than standard milk thistle capsules.

Zazzee Naturals suggests that milk thistle acts as an antioxidant by reducing free radical production, which creates a detoxifying effect in the body and supports healthy liver function.

The supplement is manufactured in the USA in a GMP-compliant facility adhering to strict quality control procedures.

The brand recommends taking one capsule up to three times a day with a meal to get the most out of the supplement.

5. Nature’s Bounty – Milk Thistle

Nature’s Bounty milk thistle utilizes rapid-release soft gels to support liver health.

Per bottle, you’ll receive 50 soft gels/servings, each containing 250mg of milk thistle extract, which is equivalent to 1,000mg whole herb.

The soft gels are designed to quickly disperse into your system to support liver function and waste elimination.

Nature’s Bounty has been manufacturing high-quality, science-backed supplements for over 40 years, and their milk thistle supplement is non-GMO and free from artificial flavors, sweeteners, and preservatives,

Nature’s Bounty recommends taking one soft gel up to three times daily for best results.

(Video) Top 10 Milk Thistle to buy in India 2021 | Price & Review

4. FarmHaven – Milk Thistle

The milk thistle capsules from FarmHaven are standardized to 80% Silymarin flavonoids and concentrated to 30:1.

You’ll receive 120 capsules/servings per bottle, each containing 375mg of organic milk thistle seed extract.

FarmHaven suggests that supplementing with milk thistle may support natural liver detoxification, provide antioxidant support, and promote a healthy inflammatory response.

The 30:1 concentration means that each capsule has the equivalent of 11,250mg of raw milk thistle seed.

The supplement is manufactured in the USA and is vegan, non-GMO, and free from gluten, soy, preservatives, and artificial ingredients.

FarmHaven recommends taking one capsule once or twice daily, depending on your tolerance and goals.

3. Jarrow Formulas – Milk Thistle

Jarrow Formulas milk thistle is a highly-concentrated formula standardized to 30:1, yielding 80% total flavonoids.

Each bottle includes 200 capsules/servings, all containing 150mg of milk thistle seed extract.

The brand suggests taking milk thistle may boost immune response, produce antioxidant and free radical scavenging activity, and induce positive liver-protecting benefits.

The supplement is produced in the brand’s GMP-compliant facility in the USA and has undergone strict testing to ensure quality and potency.

For best results, Jarrow Formulas recommends taking one to three capsules a day.

2. Puritans Pride – Milk Thistle

Puritans Pride milk thistle extract is scientifically formulated to maintain healthy liver function.

You’ll receive 180 soft gels/servings per bottle, each containing 250mg of milk thistle extract, which is equivalent to 1,000mg of the whole herb.

Puritans Pride indicates that milk thistle helps maintain healthy liver function and optimizes overall health and well-being.

The supplement is free from preservatives, artificial flavors, and sweeteners and is 100% gluten-free.

Puritans Pride recommends taking one soft gel once or twice daily, preferably with a meal, for best results.

1. Nootropics Depot – High Potency Milk Thistle

High Potency Milk Thistle Capsules (120 Count)

$29.99

Buy Now

We earn a commission if you click this link and make a purchase at no additional cost to you.

(Video) 8 Benefits of Milk Thistle for the Liver

This Milk Thistle supplement from Nootropics Depot comes in capsule format, and they focus specifically on Silymarin content, a group of bioactive constituents in milk thistle.

The claimed benefits of milk thistle stem for Silymarins, and Nootropics Depot state their high potency milk thistle has a minimum quantity per serving of 200mg Silymarins.

You can buy a bottle on their official website in either a 60 capsule count or a 120 capsule count.

The product has been lab-tested and verified for both product purity and identity.

Summary

We hope you enjoyed our list of the 10 best milk thistle supplements.

You won’t go wrong with whichever one you choose, as they’re the best milk thistle supplements on the market right now.

However, if you’re looking for our recommendation, then Puritans Pride has done us proud for years!

Here’s a quick recap of the 10 best milk thistle supplements:

(Video) Does Milk Thistle Work for the Liver?

  1. Nootropics Depot – High Potency Milk Thistle
  2. Puritans Pride – Milk Thistle
  3. Jarrow Formulas – Milk Thistle
  4. FarmHaven – Milk Thistle
  5. Nature’s Bounty – Milk Thistle
  6. Zazzee Naturals – Organic Milk Thistle
  7. Toniiq – Ultra High Strength Milk Thistle
  8. OmniBiotics – Organix Milk Thistle
  9. Bronson – Milk Thistle
  10. Nature’s Answer – Milk Thistle Extract

What’s your favorite milk thistle supplement? Leave a comment below.

FAQs

What is the safest brand of milk thistle? ›

The Best Milk Thistle Supplements
  • Best Overall. Puritan's Pride Milk Thistle. Affordable Six Month Supply. ...
  • Best Antioxidant Formula. Jarrow Formulas Milk Thistle. ...
  • Strongest Dose. Fresh Nutrition Milk Thistle Capsules. ...
  • Best for Liver Health. FarmHaven Milk Thistle Capsules. ...
  • Most Trusted. Nature's Bounty Milk Thistle Capsules.
13 Feb 2020

Which milk thistle capsule is best? ›

  • Bestseller. ...
  • Inlife Milk Thistle 400mg Capsule. ...
  • Carbamide Forte Milk Thistle Extract 600mg Vegetarian Tablet. ...
  • HealthVit Silymarin Milk Thistle 400mg Capsule. ...
  • GNC Herbal Plus Milk Thistle 250mg Capsule. ...
  • Himalayan Organics Milk Thistle 800mg Vegetarian Capsule. ...
  • Ad. ...
  • Neuherbs Milk Thistle 80% Silymarin Capsule.

What is the best amount of milk thistle to take? ›

There is no standardized dosage or recommended intake for milk thistle tea, but it's generally considered safe if consumed in moderation. Milk thistle supplements, for reference, are tolerated at doses of up to 700 mg, 3 times per day for 24 weeks ( 1 ).

Is it better to take milk thistle at night or morning? ›

Milk thistle is generally tolerated well by the body, meaning you can take it pretty much whenever you want. It won't keep you awake at night, it can be taken on an empty stomach or combined with meals as an added ingredient, and there isn't a particular time of day where it's more potent or effective.

How much milk thistle should you take daily for liver health? ›

If you're taking milk thistle for the liver, the recommended daily intake of milk thistle is 150 milligrams, taken one to three times daily. This is a somewhat high dose that can act as a natural liver detox. For ongoing use and liver support, take 50 to 150 milligrams daily.

What is the best milk thistle to take for liver? ›

Top Rated
  • Nature's Bounty Milk Thistle Capsules 250mg, 200CT. Nature's Bounty. ...
  • Nature's Truth Milk Thistle Seed Extract 1,000 mg. Nature's Truth. ...
  • Irwin Naturals Milk Thistle Liver Detox plus BioPerine Softgels, 60CT. Irwin Naturals. ...
  • CVS Health Milk Thistle Capsules, 200CT. ...
  • Nature's Bounty Milk Thistle Caplets 175mg, 100CT.

What should I avoid while taking milk thistle? ›

Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes:
  • Allergy drugs. ...
  • Drugs for high cholesterol. ...
  • Anti-anxiety drugs. ...
  • Antiplatelet and anticoagulant drugs (blood thinners). ...
  • Some cancer drugs. ...
  • Drugs broken down by the liver.

What medications should not be taken with milk thistle? ›

Possible interactions include:
  • Cytochrome P450 2C9 (CYP2C9) substrates. Taking milk thistle might affect this enzyme and drugs it processes, such as diazepam (Valium), warfarin (Jantoven) and others. ...
  • Diabetes medications. ...
  • Raloxifene (Evista). ...
  • Simeprevir. ...
  • Sirolimus (Rapamune).

What kind of milk thistle should I buy? ›

Milk thistle extract is a powerful supplement that can benefit health, especially liver health. The key to choosing the best milk thistle supplements is to look for a standardized silymarin phytosome.

What happens if you take milk thistle everyday? ›

Milk thistle is generally considered safe for most people at dosages up to 420 mg 3 times a day. However, it may cause allergic reactions, such as itching, headaches, and joint pain, or gastrointestinal symptoms like nausea or diarrhea.

How much milk thistle should I take for fatty liver? ›

Milk thistle is marketed as capsules or tablets containing ethanol extracted silymarin in amounts of 250 to 750 mg and is purported to be beneficial for liver disease, including alcoholic and viral liver disease. The daily dosage varies but it is typically taken 2 to 3 times daily.

How long can you take milk thistle safely? ›

Milk thistle is considered safe in dosages of 420 mg/day orally in divided doses for up to 41 months.

How long should you take milk thistle for liver detox? ›

Early research shows that taking milk thistle extract by mouth for up to one year, or taking a product containing the milk thistle constituent silybin plus phosphatidylcholine by mouth for 1 week, improves liver function tests.

Can milk thistle reverse liver damage? ›

Milk thistle will not reverse existing liver damage, and it will not cure infection with the hepatitis B or hepatitis C virus. Milk thistle should not be used by people who have complications from cirrhosis (such as variceal bleeding or ascites).

What are the negative side effects of milk thistle? ›

Side effects of milk thistle include:
  • Abdominal bloating/pain.
  • Allergic reactions.
  • Diarrhea.
  • Gas.
  • Indigestion.
  • Itching.
  • Loss of appetite.
  • Nausea.

What does milk thistle cure? ›

Historically, people have used milk thistle for liver disorders and gallbladder problems. Milk thistle is promoted as a dietary supplement for hepatitis, cirrhosis, jaundice, diabetes, indigestion, and other conditions.

Does milk thistle affect sleep? ›

Sleep quality also improves. The effect of taking milk thistle by itself is not known. Multiple sclerosis. Early research suggests that taking a combination supplement containing silymarin, a chemical found in milk thistle, can improve mental function and promote disease stabilization in people with multiple sclerosis.

Does milk thistle cure fatty liver? ›

Medical research on milk thistle and liver health has led to mixed results. Studies show that silymarin may help ease inflammation and promote cell repair. This may help ease symptoms from liver diseases like jaundice, cirrhosis, liver cancer, and fatty liver disease.

Does milk thistle help repair the liver? ›

Liver healing and regeneration

Milk thistle helps stop oxidative stress and free radical damage in the liver. Research shows milk thistle restores damaged cells. Silymarin also protects the liver against damage from alcohol and some prescription drugs.

Can you take milk thistle with other vitamins? ›

No interactions were found between milk thistle and Vitamins.

Is milk thistle good for your kidneys? ›

Milk thistle (Silymarin marianum) is a well-known herbal therapeutic commonly used for liver support. It supports detoxification through enhancing liver as well as kidney and pancreatic function.

Is it best to take milk thistle on an empty stomach? ›

How do I take milk thistle? Milk thistle can be taken on an empty stomach. Some believe this makes it work faster; however, very sensitive individuals should consider taking milk thistle with a meal instead. Milk thistle can be taken in herbal capsules or liquid extracts.

Does turmeric interact with milk thistle? ›

No interactions were found between milk thistle and turmeric.

Can you take milk thistle and magnesium together? ›

Interactions between your drugs

No interactions were found between milk thistle and Optimum Magnesium Gluconate. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

What does milk thistle do to the brain? ›

Improves cognition. A 2015 study in worms found that milk thistle increased resistance to oxidative stress. Oxidative stress is a potential cause of Alzheimer's disease. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind.

What organs does milk thistle help? ›

What Is Milk Thistle Used For? People have traditionally used milk thistle for problems with the liver and gallbladder . Experts believe silymarin is the primary active ingredient of the herb. Silymarin is an antioxidant compound taken from milk thistle seeds.

How can I detox my liver in 3 days? ›

The 3-day detox juice cleanse involves consuming only blended juices and water for 3 days.
...
In general, the following steps are taken in a specific order:
  1. Morning detox tea.
  2. Breakfast drink.
  3. Supplements.
  4. Lunch drink.
  5. Supplements (multivitamins, omega-3 fatty acids, and probiotics)
  6. Snack drink.
  7. Dinner drink.
  8. Detox ultra-bath.
8 Mar 2022

Is 500mg of milk thistle too much? ›

Milk thistle supplements are commonly sold as in capsule form but are also available as tablets, tea bags, and liquid extracts. Doses range from 175 milligrams to 1,000 milligrams. Milk thistle is considered safe to take daily at doses of 150 to 175 mg, three times a day.

How long does the liver take to repair? ›

The liver, however, is able to replace damaged tissue with new cells. If up to 50 to 60 percent of the liver cells may be killed within three to four days in an extreme case like a Tylenol overdose, the liver will repair completely after 30 days if no complications arise.

How do I know if my liver is detoxing? ›

10 Signs Your Liver is Detoxing
  1. Nausea.
  2. Vomiting.
  3. Anxiety.
  4. Tremors.
  5. Headache.
  6. Confusion.
  7. Insomnia.
  8. Restlessness.
22 Jun 2021

What is the best drink to flush your liver? ›

Here is a list of drinks that help in natural cleansing and detoxification of the liver according to Medical News.
  • Coffee. Coffee is good for the liver, especially because it protects against issues such as fatty liver disease. ...
  • Ginger and lemon drink. ...
  • Oatmeal drink. ...
  • Tumeric drink. ...
  • Green tea. ...
  • Grapefruit drink.
20 May 2020

Can your liver heal in 3 weeks? ›

Healing can begin as early as a few days to weeks after you stop drinking, but if the damage is severe, healing can take several months. In some cases, “if the damage to the liver has been long-term, it may not be reversible,” warns Dr. Stein.

How can I quickly repair my liver? ›

Focus on a healthy diet

getting sufficient fiber from sources like whole grains as well as fresh fruits and vegetables. choosing lean protein sources, such as seafood, skinless poultry, or legumes, as opposed to fattier meats. reducing your intake of foods or drinks that are high in sugars, salt, or unhealthy fats.

Can a damaged liver regrow? ›

The liver has a unique capacity among organs to regenerate itself after damage. A liver can regrow to a normal size even after up to 90% of it has been removed. But the liver isn't invincible. Many diseases and exposures can harm it beyond the point of repair.

Which company has best milk thistle? ›

MuscleBlaze provides the best milk thistle capsules are just the right supplement for you. Enriched with pure Silymarin, it helps boost the production of liver cells and restores any liver damage.

What is better than milk thistle for liver? ›

Like milk thistle, artichoke leaf contains the important flavonoid silymarin. Silymarin is best known for its abilities in protecting the liver. Artichoke leaf also contributes to overall health and welling by helping to maintain healthy cholesterol levels in people at risk of coronary heart disease.

What should you not take with milk thistle? ›

Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes:
  • Allergy drugs. ...
  • Drugs for high cholesterol. ...
  • Anti-anxiety drugs. ...
  • Antiplatelet and anticoagulant drugs (blood thinners). ...
  • Some cancer drugs. ...
  • Drugs broken down by the liver.

What is the best liver supplement on the market? ›

Our most recommended products for effective liver detoxification include:
  • PureHealth Research Liver Health Formula.
  • Organifi Liver Reset.
  • Zenith Labs Zenith Detox.
  • 1MD LiverMD.
  • Live Conscious LiverWell.
  • Amy Myers MD Liver Support.
  • Gundry MD Complete Liver Support.
  • Advanced Bionutritionals Advanced Liver Support.

What supplements help repair the liver? ›

Liver support herbal supplements include dandelion root, green tea, milk thistle extract and artichoke leaf. Other nutrients that also benefit the liver are vitamins C, D, and E and calcium D-glucarate.

What vitamins are good for liver repair? ›

Which Vitamins Are Good for the Liver? Vitamins that play a crucial role in maintaining liver health include vitamin D, E, C, B. Individuals need to take these vitamins regularly through a healthy diet plan.

Can I take milk thistle with vitamin d3? ›

No interactions were found between milk thistle and Vitamins.

Does milk thistle cause blood thinning? ›

Taking milk thistle might make warfarin too effective, which could increase the risk of bleeding. Before taking milk thistle, talk to your healthcare provider if you are taking warfarin.

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